However, Ca 2+ intensity within responding osteocytes did not change significantly with physiological loading magnitudes. At all loading frequencies examined, the number of responding osteocytes increased strongly with applied strain magnitude. We investigated the in vivo responses of osteocytes to strains ranging from 250 to 3,000 𝝁 ϵ and frequencies from 0.5 to 2 Hz, which are characteristic of physiological conditions reported for bone. 24 Hour Turnaround (Guaranteed) An Aerial Shot with a 30ft Tripod. Osteocyte responses are imaged by using multiphoton fluorescence microscopy. Two virtual tours (branded and unbranded). Working at IMOTO: 2 Reviews Review this company. This is achieved herein by using a three-point bending device which is capable of delivering well-defined mechanical loads to metatarsal bones of living mice while simultaneously monitoring the intracellular Ca 2+ responses of individual osteocytes by using a genetically encoded fluorescent Ca 2+ indicator. Reviews from IMOTO employees about IMOTO culture, salaries, benefits, work-life balance, management, job security, and more. Intracellular calcium (Ca 2+) signaling resulting from mechanical stimulation has been widely studied in osteocytes in vitro and in bone explants, but has yet to be examined in vivo. /rebates/&.com252fRestaurantReview-g55711-d14799107-Reviews-Imoto-DallasTexas. Osteocytes are considered to be the major mechanosensory cells of bone, but how osteocytes in vivo process, perceive, and respond to mechanical loading remains poorly understood. Kei IMOTO Family name (in kanji): Given name (in kanji): Also known as: Keiko Imoto Date of birth: XXXX-01-08 Hometown: Fukuoka, Japan.
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